兔抗eea1多---抗体

backgr

ound:

eea1 is an early endosomal marker&a rab5 effector protein essential for early endosomal membrane fusion&trafficking. the carboxy terminus of eea1 contains a fyve domain which binds to phosphatidylinositol-3-phosphate (ptdins(3)p), targeting eea1 to early endosomes. the stable asso---tion of eea1 with the endosomal membrane is regulated by pi3 kinase, rab5&calcium/calmoonce on the membrane, eea1 interacts with rab5, nsf&syntaxin 13 to promote early endosomal membrane docking&fusion.

applic

ations:

elisa, wb

name of antibody:

eea1

immu

nogen:

synthetic peptide of human eea1

full name:

early endosome antigen 1

synonyms:

mst105; zfyve2; mstp105

swissprot:

q15075

elisa recomm

ended dilution:

5000-10000

wb predicted band size:

163 kda

wb positive control:

hela, 293t, raw264.7&nih/3t3 cell lysates

wb recom

mended dilution:

200-1000